Cystic+Fibrosis

=Cystic Fibrosis by md and yr =



Cystic Fibrosis is...

 * ======Autosomal recessive genetic disorder inherited from the parents when the parents are normally heterozygous or homozygous recessive. ======
 * ======The children of a couple who are both heterozygous for CF have a 25% chance of having CF because the parents both have one recessive gene that can be inherited by their children. ======
 * ======The gene that codes for CF is located on the CFTR locus on chromosome 7, which provides instructions for making a channel that transports chloride ions in and out of cells. The flow of chloride ions contirbutes to the control the water movement in tissues, which is necessary for the production of mucus ======

Description of the symptoms/effects
X-ray of the chest of someone who has CF, where you can clearly see the mucus build up and lung problems.
 * Heavy mucus is secreted by the organs, especially in the lungs, where it can build up and can cause lung infections
 * The Diminished secretion of pancreatic enzymes is the main cause of poor growth, and deficiency in fat-soluble vitamins.
 * Males can be Infertile/Sterile

Diagnosis - what methods are used to diagnose the disorder?
 this is a young girl being treated with a breathing apparatus to help with her CF
 * There is no known cure for CF, and most individuals with cystic fibrosis die young
 * Many in their 20s and 30s from lung failure
 * With many new treatments, the life expectancy of a person with CF is increasing to ages as high as 40 or 50
 * Lung Transplantation is often necessary as CF worsens

Prognosis

 * As cystic fibrosis worsens in individuals they must get a lung transplants. But there is still no total cure for cystic fibrosis

 Statistics on the # of individuals born with the disorder

 * In the United States, 1 in 4,000 children is born with CF
 * <span style="color: rgb(255,0,255);">It is most common among western European populations
 * <span style="color: rgb(255,0,255);">One in twenty-two people of Mediterranean descent is a carrier on the gene for CF

Bibliography http://ghr.nlm.nih.gov/condition=cysticfibrosis

http://www.eradimaging.com/images/cystic_fibrosis_2008/cystic_fibrosis_fig1.jpg

http://www.wrongdiagnosis.com/c/cf/prognosis.htm

http://www.eradimaging.com/images/cystic_fibrosis_2008/cystic_fibrosis_fig1.jpg&imgrefurl=http://www.eradimaging.com/site/article.cfm%3FID%3D327&usg=__XoWFy3-cfd1lDvPcbSpQtyjAo-I=&h=478&w=421&sz=44&hl=en&start=4&um=1&tbnid=CQugFfkAHxZOCM:&tbnh=129&tbnw=114&prev=/images%3Fq%3DCystic%2BFibrosis%26hl%3Den%26safe%3Doff%26client%3Dsafari%26rls%3Den%26sa%3DG%26um%3D1

<span style="color: rgb(255,0,255);">